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KMID : 0882420140860010089
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Korean Journal of Medicine
2014 Volume.86 No. 1 p.89 ~ p.95
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A Case of Cerebellopontine Angle Diffuse Large B Cell Lymphoma in a Systemic Lupus Erythematosus Patient
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Bae Soo-Hyun
Kwon Moon-Hyuk
Kim Min-Hee
Lee Sang-Ah
Lee Jung-Lim
Han Man-Hoon
Yun Sang-Mo
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Abstract
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Patients with systemic lupus erythematosus (SLE) are at higher risk for malignant lymphomas, among which, however, primary CNS lymphoma (PCNSL) is rare. PCNSL usually occurs within the cerebral hemispheres, occasionally in the cerebellum, but rarely in the cerebellopontine angle (CPA). We report our findings in a 45-year-old man with SLE on azathioprine, who presented with sudden hearing loss and dysphagia. The brain MRI revealed a mass lesion in the right CPA. A biopsy was performed and the final diagnosis was diffuse large B cell lymphoma. This is the first report of CPA lymphoma in a SLE patient. The patient was treated with whole brain radiotherapy only because of recurrent pneumonia that was a result of dysphagia from permanent cranial nerve injury. He has been in complete remission for over 10 months.
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KEYWORD
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Diffuse large B cell lymphoma, Systemic lupus erythematosus, Hearing loss
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